Can we treat Alzheimers 20 years early? (Reisa Sperling)
Science Kit for Reisa Sperling
Hello fellow TEDMEDers:
Thanks for your interest in my talk, “Can We Treat Alzheimer’s Disease 20 Years Earlier?” at TEDMED 2012. Below are some resources that can provide additional details on our scientific work and the movement in the field towards earlier diagnosis and treatment of Alzheimer’s disease.
Here is an article that explains the concept of preclinical Alzheimer’s disease:
This article shows an example of amyloid-related brain dysfunction before memory impairment is clinically evident:
This perspectives piece describes the need to begin “secondary prevention trials” at earlier stages of AD: http://stm.sciencemag.org/content/3/111/111cm33.full
Our clinical research team works across two hospitals in Boston associated with Harvard Medical School.
To learn about clinical trials taking place at the Brigham and Women’s Hospital (BWH) with the Center for Alzheimer Research and Treatment (CART), visit: http://www.brighamandwomens.org/Research/labs/CART/default.aspx
To learn more about the Harvard Aging Brain Study at Massachusetts General Hospital, visit this site: http://www.nmr.mgh.harvard.edu/harvardagingbrain/Welcome.html
To learn more about our research at the Massaschusetts Alzheimer's Disease Research Center (ADRC), visit http://madrc.mgh.harvard.edu/
You can also find more information on Alzheimer’s disease at the
Alzheimer’s Association: http://www.alz.org/
National Institute on Aging: http://www.nia.nih.gov/alzheimers
This is a critical time in Alzheimer’s disease. As our population ages, we are truly facing a health crisis of epidemic proportions. I believe we must learn from the successes in other health fields and shift our focus towards much earlier detection and intervention. I hope that we will begin these secondary prevention trials next year, and ultimately one day prevent dementia. Thanks so much for your interest.
Reisa Sperling, M.D.
- Concepts of Preclinical Alzheimer's Disease
- Example of Amyloid-Related Brain Dysfunction before memory impairment is clinically evident
- Secondary Prevention Trials at earlier stages of AD
- Clinical trials taking place at the Brigham and Women's Hospital
- Harvard Aging Brain Study
- Massachussetts Alzheimer's Disease Research Center
- Alzheimer's Association
- National Institute on Aging